Compound Detail
CHEMBL5566958
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5566958 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DRGHOKWIQHZAGN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
422.5
MW (Da)
4.49
ALogP
2
HBA
4
HBD
86.0
PSA (Ų)
0.47
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.88
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 CHEMBL4794 | IC50 | 6.88 | 6.88 | 130.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | IC50 | = | 130.9 | nM | 6.88 | Antagonist activity at human TRPV1 receptor assessed as inhibition of TRPV1 chan... | 38325006 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38325006 | 10.1016/j.ejmech.2024.116208 | Transient receptor potential cation channel subfamily V member 1 | 1 |
| 38325006 | 10.1016/j.ejmech.2024.116208 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine