Compound Detail
CHEMBL5567128
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5567128 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTFFENXGBPVGOQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
326.8
MW (Da)
2.89
ALogP
4
HBA
1
HBD
59.8
PSA (Ų)
0.78
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Receptor-interacting serine/threonine-protein kinase 1 CHEMBL5464 | IC50 | 6.6 | 6.6 | 250.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Receptor-interacting serine/threonine-protein kinase 1 | IC50 | = | 250.0 | nM | 6.6 | Inhibition of RIPK1 (unknown origin) | 38199165 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38199165 | 10.1016/j.ejmech.2024.116123 | Receptor-interacting serine/threonine-protein kinase 1 | 1 |
| 38199165 | 10.1016/j.ejmech.2024.116123 | Receptor-interacting serine/threonine-protein kinase 3 | 1 |
Data from ChEMBL 36 via Core Engine