Compound Detail
CHEMBL5591474
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CCCCC[C@@H]1NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H](C)N(C)C(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2cscn2)NC(=O)[C@H](C)N(C)C(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](CC(CC)CC)N(C)C1=O
Basic Information
| ChEMBL ID | CHEMBL5591474 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GIDRLHRXJFUPCX-DCMWNUTASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1138.5
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein Mdm4 CHEMBL1255126 | IC50 | 7.16 | 7.16 | 70.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein Mdm4 | IC50 | = | 70.0 | nM | 7.16 | Inhibition of MDMX (unknown origin) | 39185935 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39185935 | 10.1021/acs.jmedchem.4c00913 | Protein Mdm4 | 1 |
Data from ChEMBL 36 via Core Engine