Compound Detail
CHEMBL560418
8-HYDROXYCANNABINOLIC ACID A Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL560418 |
| Name | 8-HYDROXYCANNABINOLIC ACID A |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DMVDJDMFQCOKJW-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
370.4
MW (Da)
5.13
ALogP
4
HBA
3
HBD
87.0
PSA (Ų)
0.64
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Staphylococcus aureus CHEMBL352 | IC50 | 5.46 | 5.46 | 3500.0 | 1 |
| Escherichia coli CHEMBL354 | IC50 | 4.27 | 4.27 | 54000.0 | 1 |
| Pichia kudriavzevii CHEMBL612841 | IC50 | 4.27 | 4.27 | 54000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Staphylococcus aureus | IC50 | = | 3500.0 | nM | 5.46 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by alamar blue a... | 19344127 |
| Pichia kudriavzevii | IC50 | = | 54000.0 | nM | 4.27 | Antifungal activity against Candida krusei ATCC 6258 by alamar blue assay | 19344127 |
| Escherichia coli | IC50 | = | 54000.0 | nM | 4.27 | Antibacterial activity against Escherichia coli ATCC 35218 after 18 to 24 hrs by... | 19344127 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19344127 | 10.1021/np900067k | Staphylococcus aureus | 2 |
| 19344127 | 10.1021/np900067k | Pichia kudriavzevii | 1 |
| 19344127 | 10.1021/np900067k | Escherichia coli | 1 |
| 19344127 | 10.1021/np900067k | Candida albicans | 1 |
| 19344127 | 10.1021/np900067k | Mycobacterium intracellulare | 1 |
| 19344127 | 10.1021/np900067k | Vero | 1 |
Data from ChEMBL 36 via Core Engine