Compound Detail
CHEMBL5612036
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Basic Information
| ChEMBL ID | CHEMBL5612036 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RUCYWKIPKMCRTR-LLVKDONJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
393.4
MW (Da)
3.77
ALogP
6
HBA
2
HBD
71.8
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MAP kinase-activated protein kinase 2 CHEMBL2208 | IC50 | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MAP kinase-activated protein kinase 2 | IC50 | = | 1.0 | nM | 9.0 | Inhibition of MK2 (unknown origin) using ST3-Sox peptide as substrate measured f... | 39291023 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39291023 | 10.1021/acsmedchemlett.4c00393 | MAP kinase-activated protein kinase 2 | 1 |
Data from ChEMBL 36 via Core Engine