Compound Detail
CHEMBL5619500
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Basic Information
| ChEMBL ID | CHEMBL5619500 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LBBCHLHLCJAAPR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
400.5
MW (Da)
5.16
ALogP
5
HBA
1
HBD
69.0
PSA (Ų)
0.44
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nuclear receptor subfamily 2 group E member 1 CHEMBL1961788 | EC50 | 6.89 | 6.89 | 130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nuclear receptor subfamily 2 group E member 1 | EC50 | = | 130.0 | nM | 6.89 | Agonist activity at human TLX LBD expressed in HEK293T cells co-transfected with... | 39236094 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 39236094 | 10.1021/acs.jmedchem.4c01443 | Nuclear receptor subfamily 2 group E member 1 | 2 |
Data from ChEMBL 36 via Core Engine