Compound Detail
CHEMBL5630254
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Basic Information
| ChEMBL ID | CHEMBL5630254 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JDCCNMXSIZZJJE-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
324.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.01 | 4.4733 | 9760.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 9760.0 | nM | 5.01 | Inhibition of recombinant his tagged VIM-2 (unknown origin) expressed in Escheri... | 37209449 |
| Unchecked | IC50 | = | 48040.0 | nM | 4.32 | Inhibition of recombinant NDM1 (unknown origin) expressed in Escherichia coli (D... | 37209449 |
| Unchecked | IC50 | = | 81100.0 | nM | 4.09 | Inhibition of recombinant VIM-5 (unknown origin) expressed in Escherichia coli (... | 37209449 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37209449 | 10.1016/j.ejmech.2023.115473 | Unchecked | 5 |
| 37209449 | 10.1016/j.ejmech.2023.115473 | Escherichia coli | 5 |
| 37209449 | 10.1016/j.ejmech.2023.115473 | Enterobacterales | 2 |
| 37209449 | 10.1016/j.ejmech.2023.115473 | Klebsiella pneumoniae | 1 |
Data from ChEMBL 36 via Core Engine