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Compound Detail

CHEMBL5630332

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OB(O)c1cccc(-c2cn(-c3cccc(Cl)c3)nn2)c1

Basic Information

ChEMBL ID CHEMBL5630332
Phase Preclinical
Structure Type MOL
InChI Key JNTZKTDRFULHNG-UHFFFAOYSA-N
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

299.5
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C14H11BClN3O2
MW 299.53

Activity Summary

IC50 3 meas. best 4.83

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 4.83 4.6633 14660.0 3

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
37209449 10.1016/j.ejmech.2023.115473 Unchecked 5

Data from ChEMBL 36 via Core Engine