Compound Detail
CHEMBL5630422
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Basic Information
| ChEMBL ID | CHEMBL5630422 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QRCRHHUPIOWOOO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
308.3
MW (Da)
2.82
ALogP
5
HBA
2
HBD
81.4
PSA (Ų)
0.85
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| CDGSH iron-sulfur domain-containing protein 2 CHEMBL4523399 | EC50 | 7.47 | 7.47 | 34.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| CDGSH iron-sulfur domain-containing protein 2 | EC50 | = | 34.0 | nM | 7.47 | Activation of Cisd2 (unknown origin) transfected in HEK293 cells incubated for 2... | 37393792 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37393792 | 10.1016/j.ejmech.2023.115583 | ADMET | 17 |
| 37393792 | 10.1016/j.ejmech.2023.115583 | Mus musculus | 8 |
| 37393792 | 10.1016/j.ejmech.2023.115583 | CDGSH iron-sulfur domain-containing protein 2 | 1 |
Data from ChEMBL 36 via Core Engine