Compound Detail
CHEMBL568489
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL568489 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WPQNWDPAOCIOFM-DOFZRALJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
368.6
MW (Da)
4.93
ALogP
2
HBA
2
HBD
72.2
PSA (Ų)
0.30
QED
0
Ro5 Violations
16
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL3571 | Ki | 5.4 | 5.4 | 4010.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | Ki | = | 4010.0 | nM | 5.4 | Displacement of [3H]SR141716A from CB1 receptor in rat cerebellar membrane after... | 19762126 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19762126 | 10.1016/j.ejmech.2009.08.003 | Cannabinoid receptor 1 | 2 |
| 19762126 | 10.1016/j.ejmech.2009.08.003 | Fatty-acid amide hydrolase 1 | 1 |
Data from ChEMBL 36 via Core Engine