Compound Detail
CHEMBL571475
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL571475 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DSYPQNCLZHZVKW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
364.4
MW (Da)
2.71
ALogP
5
HBA
1
HBD
52.5
PSA (Ų)
0.60
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 3A CHEMBL2411 | Ki | 6.48 | 6.48 | 330.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 3A | Ki | = | 330.2 | nM | 6.48 | Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate | 19831400 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19831400 | 10.1021/jm901126m | 5-hydroxytryptamine receptor 3A | 1 |
Data from ChEMBL 36 via Core Engine