Compound Detail
CHEMBL5723340
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Basic Information
| ChEMBL ID | CHEMBL5723340 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QPHXOGYKQZAYFS-UHFFFAOYSA-N |
| Parent Compound | CHEMBL2220483 |
| Active Moiety | CHEMBL2220483 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
302.4
MW (Da)
3.47
ALogP
5
HBA
2
HBD
76.2
PSA (Ų)
0.34
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Complement C1s subcomponent CHEMBL3913 | IC50 | 8.8 | 8.8 | 1.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Complement C1s subcomponent | IC50 | = | 1.6 | nM | 8.8 | Affinity Biochemical interaction: (inhibition of substrate cleavage, coloured en... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL5723035 | Complement C1s subcomponent | 1 |
Data from ChEMBL 36 via Core Engine