Compound Detail
CHEMBL573448
LACTISOLE Phase I
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Phase I
Basic Information
| ChEMBL ID | CHEMBL573448 |
| Name | LACTISOLE |
| Phase | Phase I |
| Structure Type | MOL |
| InChI Key | MIEKOFWWHVOKQX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
2
Known Names
Molecular Properties
196.2
MW (Da)
1.55
ALogP
3
HBA
1
HBD
55.8
PSA (Ų)
0.79
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Activity Summary
IC50 1 meas. best 4.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.16 | 4.16 | 70000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 70000.0 | nM | 4.16 | Antagonist activity at human T1R2/T1R3 receptor expressed in HEK293E cells asses... | 19817384 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19817384 | 10.1021/jm900823s | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine