Compound Detail
CHEMBL574285
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Basic Information
| ChEMBL ID | CHEMBL574285 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IPWNDJWJXCLYIL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
391.9
MW (Da)
4.31
ALogP
6
HBA
3
HBD
91.4
PSA (Ų)
0.43
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Casein kinase II subunit alpha CHEMBL3629 | IC50 | 5.5 | 5.5 | 3200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Casein kinase II subunit alpha | IC50 | = | 3200.0 | nM | 5.5 | Inhibition of Zea mays CK2alpha | 12816539 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12816539 | 10.1042/bj20030674 | Casein kinase II subunit alpha | 1 |
Data from ChEMBL 36 via Core Engine