Compound Detail
CHEMBL5754510
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CN(C)S(=O)(=O)c1cccc(S(=O)(=O)c2ccc(CNC(=NC#N)Nc3ccncc3)cc2)c1
Basic Information
| ChEMBL ID | CHEMBL5754510 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NAKQLVMQWLONBV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
498.6
MW (Da)
2.20
ALogP
7
HBA
2
HBD
144.6
PSA (Ų)
0.29
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nicotinamide phosphoribosyltransferase CHEMBL1744525 | IC50 | 8.89 | 8.89 | 1.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nicotinamide phosphoribosyltransferase | IC50 | = | 1.3 | nM | 8.89 | Biochemical Inhibition Assay: The NAMPT enzymatic reactions were carried out in ... | - |
Data from ChEMBL 36 via Core Engine