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Compound Detail

CHEMBL5759956

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CC(C)(C)C(=O)Nc1cccc(CCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)c1

Basic Information

ChEMBL ID CHEMBL5759956
Phase Preclinical
Structure Type MOL
InChI Key QQEXBMATSYAASX-XMTFNYHQSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

380.5
MW (Da)
0.36
ALogP
6
HBA
5
HBD
113.3
PSA (Ų)
0.49
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H32N2O5
MW 380.49
Aromatic Rings 1
Heavy Atoms 27
NP-Likeness 0.03

Activity Summary

EC50 1 meas. best 5.62

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 5.62 5.62 2400.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked EC50 = 2400.0 nM 5.62 BVDV antiviral and plaque assays: To evaluate antiviral activity against BVDV, a... -

Data from ChEMBL 36 via Core Engine