Compound Detail
CHEMBL5765924
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Basic Information
| ChEMBL ID | CHEMBL5765924 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WELJFAFWZSRQSH-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
344.4
MW (Da)
2.88
ALogP
6
HBA
2
HBD
78.3
PSA (Ų)
0.89
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 9.06
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein O-GlcNAcase CHEMBL5921 | Ki | 9.06 | 9.01 | 0.9 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein O-GlcNAcase | Ki | = | 0.861 | nM | 9.06 | Assay for Determination of KI Values for Inhibition of O-GlcNAcase Activity : Ex... | - |
| Protein O-GlcNAcase | Ki | = | 1.09 | nM | 8.96 | Assay for Determination of KI Values for Inhibition of O-GlcNAcase Activity : Ex... | - |
Data from ChEMBL 36 via Core Engine