Compound Detail
CHEMBL5771022
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CC(=O)Nc1cc(NC(C)=O)cc(S(=O)(=O)c2cccc3c(=O)n(O)c(=O)[nH]c23)c1
Basic Information
| ChEMBL ID | CHEMBL5771022 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YUWNYQCMYAUWPO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
432.4
MW (Da)
0.68
ALogP
8
HBA
4
HBD
167.4
PSA (Ų)
0.44
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Flap endonuclease 1 CHEMBL5027 | IC50 | 8.12 | 8.12 | 7.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Flap endonuclease 1 | IC50 | = | 7.6 | nM | 8.12 | Enzymatic Assay: Fluorogenic biochemical assays used recombinant full-length FEN... | - |
Data from ChEMBL 36 via Core Engine