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Compound Detail

CHEMBL5778555

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CC.O=c1[nH]c2cccc(-c3ccc(F)cc3)c2cc1O

Basic Information

ChEMBL ID CHEMBL5778555
Phase Preclinical
Structure Type MOL
InChI Key UAUVWCUYDOZAEE-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

285.3
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H16FNO2
MW 285.32

Activity Summary

IC50 1 meas. best 5.48

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.48 5.48 3300.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked IC50 = 3300.0 nM 5.48 Endonuclease Assay: The PAN domain has been shown to cleave ssRNA as well as ssD... -

Data from ChEMBL 36 via Core Engine