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Compound Detail

CHEMBL5790523

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COc1ccccc1CC(=O)N[C@@H](Cc1coc2ccccc12)B(O)O

Basic Information

ChEMBL ID CHEMBL5790523
Phase Preclinical
Structure Type MOL
InChI Key PTDOVQKEBNAMSD-SFHVURJKSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

353.2
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H20BNO5
MW 353.18

Activity Summary

IC50 1 meas. best 6.56

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Proteasome Macropain subunit MB1
CHEMBL4662
IC50 6.56 6.56 275.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine