Compound Detail
CHEMBL5807279
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Basic Information
| ChEMBL ID | CHEMBL5807279 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CHLXVWPOHSBADP-KMMAFYGUSA-N |
1
Targets
4
Activities
3
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
415.6
MW (Da)
4.59
ALogP
3
HBA
2
HBD
77.8
PSA (Ų)
0.34
QED
0
Ro5 Violations
14
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas.
IC50 1 meas. best 8.24
Ki 1 meas. best 8.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP4 subtype CHEMBL1836 | Ki | 8.68 | 8.68 | 2.1 | 1 |
| Prostaglandin E2 receptor EP4 subtype CHEMBL1836 | IC50 | 8.24 | 8.24 | 5.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin E2 receptor EP4 subtype | Ki | = | 2.1 | nM | 8.68 | Radioligand Binding Assay: 200 μl in 96-well plate. Cell membrane homogenates (2... | - |
| Prostaglandin E2 receptor EP4 subtype | IC50 | = | 5.7 | nM | 8.24 | Radioligand Binding Assay: 200 μl in 96-well plate. Cell membrane homogenates (2... | - |
Data from ChEMBL 36 via Core Engine