Compound Detail
CHEMBL5818097
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Basic Information
| ChEMBL ID | CHEMBL5818097 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZAPSJAGEHKLHMT-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
347.5
MW (Da)
4.97
ALogP
2
HBA
2
HBD
45.0
PSA (Ų)
0.70
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.44
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Complement factor B CHEMBL5731 | IC50 | 7.44 | 5.94 | 36.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Complement factor B | IC50 | = | 36.0 | nM | 7.44 | Human Complement Factor B TR-FRET Assay: CVF-Bb complex prepared from purified c... | - |
| Complement factor B | IC50 | = | 36000.0 | nM | 4.44 | Human Complement Factor B TR-FRET Assay: CVF-Bb complex prepared from purified c... | - |
Data from ChEMBL 36 via Core Engine