Compound Detail
CHEMBL5835028
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Basic Information
| ChEMBL ID | CHEMBL5835028 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YYBCNHLZAHJUAY-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
346.4
MW (Da)
2.88
ALogP
4
HBA
1
HBD
47.1
PSA (Ų)
0.93
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Short transient receptor potential channel 6 CHEMBL2417347 | IC50 | 8.47 | 8.47 | 3.4 | 1 |
| Short transient receptor potential channel 3 CHEMBL2417348 | IC50 | 8.18 | 8.18 | 6.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Short transient receptor potential channel 6 | IC50 | = | 3.4 | nM | 8.47 | Electrophysiology Assay: For TRPC6 current recording, the intracellular solution... | - |
| Short transient receptor potential channel 3 | IC50 | = | 6.64 | nM | 8.18 | Electrophysiology Assay: For TRPC6 current recording, the intracellular solution... | - |
Data from ChEMBL 36 via Core Engine