Compound Detail
CHEMBL5843160
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5843160 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MZQGLZHSAPWTKF-ZIAGYGMSSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
323.4
MW (Da)
1.92
ALogP
4
HBA
2
HBD
63.2
PSA (Ų)
0.87
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.2
IC50 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | EC50 | 8.2 | 8.2 | 6.3 | 1 |
| Somatostatin receptor type 4 CHEMBL1853 | IC50 | 6.8 | 6.8 | 158.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | EC50 | = | 6.31 | nM | 8.2 | Inhibition of Forskolin Stimulated cAMP in Cells Overexpressing SSTR4: This cell... | - |
| Somatostatin receptor type 4 | IC50 | = | 158.0 | nM | 6.8 | SSTR4 I-125 Somatostatin Competition Binding Assay: This membrane-based assay me... | - |
Data from ChEMBL 36 via Core Engine