Compound Detail
CHEMBL584704
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Basic Information
| ChEMBL ID | CHEMBL584704 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JLNDFPWHZBHHAB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
500.6
MW (Da)
6.32
ALogP
6
HBA
0
HBD
62.6
PSA (Ų)
0.21
QED
2
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor alpha CHEMBL239 | EC50 | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor alpha | EC50 | = | 300.0 | nM | 6.52 | Agonist activity at PPARalpha assessed as receptor transactivation by reporter g... | 20073471 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20073471 | 10.1021/jm901272d | Peroxisome proliferator-activated receptor gamma | 2 |
| 20073471 | 10.1021/jm901272d | Peroxisome proliferator-activated receptor alpha | 2 |
| 20073471 | 10.1021/jm901272d | Type-1 angiotensin II receptor A | 1 |
Data from ChEMBL 36 via Core Engine