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Compound Detail

CHEMBL5847048

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CN(C1CCCC1Oc1nc(Nc2ccc3c(c2)OCCOCCOCCO3)nc2[nH]ccc12)S(C)(=O)=O

Basic Information

ChEMBL ID CHEMBL5847048
Phase Preclinical
Structure Type MOL
InChI Key JPYUEXJVTHUHFS-UHFFFAOYSA-N
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

547.6
MW (Da)
2.70
ALogP
10
HBA
2
HBD
137.1
PSA (Ų)
0.47
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C25H33N5O7S
MW 547.63
Aromatic Rings 3
Heavy Atoms 38
NP-Likeness -0.86

Activity Summary

IC50 3 meas. best 7.9

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Focal adhesion kinase 1
CHEMBL2695
IC50 7.9 7.9 12.7 3

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine