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Compound Detail

CHEMBL5848541

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CC(C)(C)C(=O)N(CCCCCCN1[C@H](CO)[C@@H](O)[C@H](O)[C@H]1CO)C1CCCCC1

Basic Information

ChEMBL ID CHEMBL5848541
Phase Preclinical
Structure Type MOL
InChI Key BVDBYEVLAKKNLU-XRXFAXGQSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

428.6
MW (Da)
1.51
ALogP
6
HBA
4
HBD
104.5
PSA (Ų)
0.39
QED
0
Ro5 Violations
10
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H44N2O5
MW 428.61
Aromatic Rings 0
Heavy Atoms 30
NP-Likeness -0.13

Activity Summary

EC50 1 meas. best 4.68

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 4.68 4.68 21000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked EC50 = 21000.0 nM 4.68 BVDV antiviral and plaque assays: To evaluate antiviral activity against BVDV, a... -

Data from ChEMBL 36 via Core Engine