Compound Detail
CHEMBL5851425
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Basic Information
| ChEMBL ID | CHEMBL5851425 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DQSDTWNNUBVZJC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
324.4
MW (Da)
2.98
ALogP
5
HBA
1
HBD
73.4
PSA (Ų)
0.87
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-secretase 1 CHEMBL4822 | IC50 | 6.11 | 6.11 | 770.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-secretase 1 | IC50 | = | 770.0 | nM | 6.11 | TR-FRET Assay: The cDNA for the soluble part of the human 13-Secretase (AA 1-AA ... | - |
Data from ChEMBL 36 via Core Engine