Compound Detail
CHEMBL5852017
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Basic Information
| ChEMBL ID | CHEMBL5852017 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GKBPVOSOOLIKMQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
327.3
MW (Da)
2.04
ALogP
7
HBA
2
HBD
94.1
PSA (Ų)
0.76
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A CHEMBL3535 | IC50 | 7.4 | 7.4 | 40.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | IC50 | = | 40.0 | nM | 7.4 | Inhibition Assay: Inhibition activities of all the N-substituted pyrazolo [3,4-d... | - |
Data from ChEMBL 36 via Core Engine