Compound Detail
CHEMBL5854380
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Basic Information
| ChEMBL ID | CHEMBL5854380 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SQZYZFVVZHQAKQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
427.4
MW (Da)
4.52
ALogP
6
HBA
3
HBD
92.1
PSA (Ų)
0.33
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histone deacetylase 11 CHEMBL3310 | IC50 | 6.12 | 6.12 | 750.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histone deacetylase 11 | IC50 | = | 750.0 | nM | 6.12 | HDAC Inhibition Assays: This example describes in vitro inhibition properties of... | - |
| Histone deacetylase 11 | IC50 | = | 750.0 | nM | 6.12 | Time Resolved Fluorescence (TRF) Assay: The probe binding HDAC11 assay was perfo... | - |
Data from ChEMBL 36 via Core Engine