Compound Detail
CHEMBL5858085
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Basic Information
| ChEMBL ID | CHEMBL5858085 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VGMATMOYFFGPAE-IUCAKERBSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
387.3
MW (Da)
1.81
ALogP
5
HBA
2
HBD
72.5
PSA (Ų)
0.73
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.1
IC50 1 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | EC50 | 8.1 | 8.1 | 7.9 | 1 |
| Somatostatin receptor type 4 CHEMBL1853 | IC50 | 7.6 | 7.6 | 25.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | EC50 | = | 7.94 | nM | 8.1 | Inhibition of Forskolin Stimulated cAMP in Cells Overexpressing SSTR4: This cell... | - |
| Somatostatin receptor type 4 | IC50 | = | 25.1 | nM | 7.6 | SSTR4 I-125 Somatostatin Competition Binding Assay: This membrane-based assay me... | - |
Data from ChEMBL 36 via Core Engine