Compound Detail
CHEMBL5866011
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Basic Information
| ChEMBL ID | CHEMBL5866011 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CUCZGBPXEVFAAI-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
381.5
MW (Da)
3.14
ALogP
7
HBA
3
HBD
114.5
PSA (Ų)
0.50
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 9.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase receptor Ret CHEMBL2041 | IC50 | 9.55 | 9.55 | 0.3 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase receptor Ret | IC50 | = | 0.279 | nM | 9.55 | Inhibitory Activity Assay: To measure the inhibitory activity, first, the compou... | - |
| Proto-oncogene tyrosine-protein kinase receptor Ret | IC50 | = | 0.279 | nM | 9.55 | Inhibitory Activity Assay: To measure the inhibitory activity, first, the compou... | - |
Data from ChEMBL 36 via Core Engine