Compound Detail
CHEMBL5870151
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Basic Information
| ChEMBL ID | CHEMBL5870151 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JTMAGZLVVBRGSP-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
348.4
MW (Da)
1.67
ALogP
6
HBA
1
HBD
72.9
PSA (Ų)
0.91
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Short transient receptor potential channel 3 CHEMBL2417348 | IC50 | 8.39 | 8.39 | 4.0 | 1 |
| Short transient receptor potential channel 6 CHEMBL2417347 | IC50 | 7.97 | 7.97 | 10.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Short transient receptor potential channel 3 | IC50 | = | 4.03 | nM | 8.39 | Electrophysiology Assay: For TRPC6 current recording, the intracellular solution... | - |
| Short transient receptor potential channel 6 | IC50 | = | 10.6 | nM | 7.97 | Electrophysiology Assay: For TRPC6 current recording, the intracellular solution... | - |
Data from ChEMBL 36 via Core Engine