Compound Detail
CHEMBL5874446
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Basic Information
| ChEMBL ID | CHEMBL5874446 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PCINBSQTEDBZDB-ITGUQSILSA-N |
1
Targets
5
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
289.4
MW (Da)
1.13
ALogP
4
HBA
2
HBD
63.2
PSA (Ų)
0.85
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 7.4
EC50 2 meas. best 8.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 4 CHEMBL1853 | EC50 | 8.43 | 8.43 | 3.7 | 2 |
| Somatostatin receptor type 4 CHEMBL1853 | Ki | 7.4 | 7.4 | 39.9 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 4 | EC50 | = | 3.7 | nM | 8.43 | AMP Assay with Human Somatostatin 4 Receptor: The activation of the SSTR4 recept... | - |
| Somatostatin receptor type 4 | EC50 | = | 3.7 | nM | 8.43 | cAMP ASSAY: The activation of the SSTR4 receptor (Gi coupled) causes an inhibiti... | - |
| Somatostatin receptor type 4 | Ki | = | 39.9 | nM | 7.4 | Radiogland Binding Assays: For the binding experiments 200 μL of membrane homoge... | - |
| Somatostatin receptor type 4 | Ki | = | 39.9 | nM | 7.4 | Radioligand Binding Assay: Receptor binding assays refer to a technique in which... | - |
| Somatostatin receptor type 4 | Ki | = | 39.9 | nM | 7.4 | Radioligand Binding Assays: Receptor binding assays refer to a technique in whic... | - |
Data from ChEMBL 36 via Core Engine