Compound Detail
CHEMBL5874804
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CS(=O)(=O)c1ccc(Nc2nc(N)c3c(n2)n(C2CCCC2)c(=O)n3-c2cccc3[nH]ncc23)c(F)c1
Basic Information
| ChEMBL ID | CHEMBL5874804 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HYUANFDZLDNNRO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
522.6
MW (Da)
3.44
ALogP
10
HBA
3
HBD
153.6
PSA (Ų)
0.32
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein-tyrosine kinase 6 CHEMBL4601 | IC50 | 8.7 | 8.7 | 2.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein-tyrosine kinase 6 | IC50 | = | 2.0 | nM | 8.7 | Measurement of Brk Inhibitory Activity: Measurement of an inhibitory activity on... | - |
Data from ChEMBL 36 via Core Engine