Compound Detail
CHEMBL5882020
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Basic Information
| ChEMBL ID | CHEMBL5882020 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UKFMFQUZEVBPRN-MRXNPFEDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
383.5
MW (Da)
1.47
ALogP
9
HBA
3
HBD
117.0
PSA (Ų)
0.55
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase Chk1 CHEMBL4630 | IC50 | 7.64 | 7.64 | 23.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase Chk1 | IC50 | = | 23.0 | nM | 7.64 | Caliper Assay: CHK1 kinase activity was measured in a microfluidic assay that mo... | - |
Data from ChEMBL 36 via Core Engine