Compound Detail
CHEMBL5907906
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Basic Information
| ChEMBL ID | CHEMBL5907906 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IDFWOLDHCSUASK-UHFFFAOYSA-N |
2
Targets
6
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
491.6
MW (Da)
4.29
ALogP
10
HBA
3
HBD
114.3
PSA (Ų)
0.31
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 6 meas. best 8.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Interleukin-6 CHEMBL1795129 | EC50 | 8.16 | 7.6 | 6.9 | 3 |
| Toll-like receptor 7 CHEMBL5936 | EC50 | 8.12 | 7.6467 | 7.5 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Interleukin-6 | EC50 | = | 6.9 | nM | 8.16 | Interleukin 6 Induction Assay: Compounds diluted in DMSO were transferred to ind... | - |
| Toll-like receptor 7 | EC50 | = | 7.5 | nM | 8.12 | TLR7 Agonist Activity Assay: Engineered human embryonic kidney blue cells (HEK-B... | - |
| Toll-like receptor 7 | EC50 | = | 39.0 | nM | 7.41 | TLR7 Agonist Activity Assay: Engineered human embryonic kidney blue cells (HEK-B... | - |
| Toll-like receptor 7 | EC50 | = | 39.0 | nM | 7.41 | TLR7 Agonist Activity Assay: Engineered human embryonic kidney blue cells (HEK-B... | - |
| Interleukin-6 | EC50 | = | 48.0 | nM | 7.32 | Interleukin 6 Induction Assay: Compounds diluted in DMSO were transferred to ind... | - |
| Interleukin-6 | EC50 | = | 48.0 | nM | 7.32 | Interleukin 6 Induction Assay: Compounds diluted in DMSO were transferred to ind... | - |
Data from ChEMBL 36 via Core Engine