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Compound Detail

CHEMBL5925613

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CN([C@@H]1CCCC[C@H]1Oc1nc(Nc2ccc3c(c2)OCCOCCOCCO3)nc2[nH]ccc12)S(C)(=O)=O

Basic Information

ChEMBL ID CHEMBL5925613
Phase Preclinical
Structure Type MOL
InChI Key QJFVHSHISHMZHZ-NHCUHLMSSA-N
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

561.7
MW (Da)
3.09
ALogP
10
HBA
2
HBD
137.1
PSA (Ų)
0.46
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H35N5O7S
MW 561.66
Aromatic Rings 3
Heavy Atoms 39
NP-Likeness -0.86

Activity Summary

IC50 3 meas. best 7.46

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Focal adhesion kinase 1
CHEMBL2695
IC50 7.46 7.46 34.9 3

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine