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Compound Detail

CHEMBL5928312

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C.CCCc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(C)(C)NC[C@@H]2C)C3(C)C)n1

Basic Information

ChEMBL ID CHEMBL5928312
Phase Preclinical
Structure Type MOL
InChI Key HCVHDJCKBSUQEW-ZOWNYOTGSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

460.6
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C23H37FN8O
MW 460.60

Activity Summary

Ki 1 meas. best 8.76

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 8.76 8.76 1.7 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked Ki = 1.73 nM 8.76 Inhibition Assay: Protein Kinase C beta 2 (PKCβII) catalyzes the production of A... -

Data from ChEMBL 36 via Core Engine