Compound Detail
CHEMBL5928490
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Basic Information
| ChEMBL ID | CHEMBL5928490 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MIKLHKPQEFLMJR-NSCUHMNNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
252.7
MW (Da)
3.70
ALogP
3
HBA
1
HBD
63.6
PSA (Ų)
0.90
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transthyretin CHEMBL3194 | IC50 | 5.6 | 5.6 | 2490.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transthyretin | IC50 | = | 2490.0 | nM | 5.6 | In vitro evaluation of inhibitory activity against WT-TTR: In vitro evaluation o... | - |
Data from ChEMBL 36 via Core Engine