Compound Detail
CHEMBL5939909
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Basic Information
| ChEMBL ID | CHEMBL5939909 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PIYZASGZELZCSC-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
244.2
MW (Da)
0.79
ALogP
3
HBA
3
HBD
82.2
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.28
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Indoleamine 2,3-dioxygenase 1 CHEMBL4685 | IC50 | 4.28 | 4.28 | 53000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Indoleamine 2,3-dioxygenase 1 | IC50 | = | 53000.0 | nM | 4.28 | Assay for IDO1 Enzymatic Activity Determination: To measure enzymatic activity o... | - |
| Indoleamine 2,3-dioxygenase 1 | IC50 | = | 53000.0 | nM | 4.28 | Enzymatic Activity Assay: The compounds of the present invention inhibit the enz... | - |
Data from ChEMBL 36 via Core Engine