Compound Detail
CHEMBL5967345
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Basic Information
| ChEMBL ID | CHEMBL5967345 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GFOJWGYPLGSKOJ-UHFFFAOYSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
408.5
MW (Da)
2.42
ALogP
8
HBA
1
HBD
110.1
PSA (Ų)
0.67
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 9.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 9.25 | 8.75 | 0.6 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform CHEMBL3130 | Ki | 8.77 | 8.4 | 1.7 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 0.56 | nM | 9.25 | p110alpha (Alpha) PI3K Binding Assay: PI3K Binding assays are intended for deter... | - |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Ki | = | 1.7 | nM | 8.77 | p110alpha (Alpha) PI3K Binding Assay: PI3K Binding assays are intended for deter... | - |
| Unchecked | Ki | = | 5.66 | nM | 8.25 | p110alpha (Alpha) PI3K Binding Assay: PI3K Binding assays are intended for deter... | - |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Ki | = | 9.41 | nM | 8.03 | p110alpha (Alpha) PI3K Binding Assay: PI3K Binding assays are intended for deter... | - |
Data from ChEMBL 36 via Core Engine