Compound Detail
CHEMBL5976223
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Basic Information
| ChEMBL ID | CHEMBL5976223 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MVSORFAXECVTFK-BQUFFADESA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
285.3
MW (Da)
3.12
ALogP
4
HBA
0
HBD
47.8
PSA (Ų)
0.81
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Receptor-interacting serine/threonine-protein kinase 1 CHEMBL5464 | Ki | 8.43 | 8.125 | 3.7 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Receptor-interacting serine/threonine-protein kinase 1 | Ki | = | 3.7 | nM | 8.43 | Enzyme Assay: The ability of the receptor interacting protein kinase (RIPK1) to ... | - |
| Receptor-interacting serine/threonine-protein kinase 1 | Ki | = | 15.0 | nM | 7.82 | Enzyme Assay: The ability of the receptor interacting protein kinase (RIPK1) to ... | - |
Data from ChEMBL 36 via Core Engine