Compound Detail
CHEMBL5981804
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Basic Information
| ChEMBL ID | CHEMBL5981804 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTZIJSWOJBPQBP-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
404.5
MW (Da)
5.30
ALogP
3
HBA
2
HBD
65.6
PSA (Ų)
0.61
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 11.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Complement factor B CHEMBL5731 | IC50 | 11.0 | 9.48 | 0.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Complement factor B | IC50 | = | 0.01 | nM | 11.0 | Human Complement Factor B TR-FRET Assay: CVF-Bb complex prepared from purified c... | - |
| Complement factor B | IC50 | = | 11.0 | nM | 7.96 | Human Complement Factor B TR-FRET Assay: CVF-Bb complex prepared from purified c... | - |
Data from ChEMBL 36 via Core Engine