Compound Detail
CHEMBL6003906
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Basic Information
| ChEMBL ID | CHEMBL6003906 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QXGWFGOTMGPLKW-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
392.5
MW (Da)
3.55
ALogP
6
HBA
1
HBD
86.1
PSA (Ų)
0.69
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 8.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A CHEMBL2292 | EC50 | 8.77 | 8.77 | 1.7 | 1 |
| Glycogen synthase kinase-3 beta CHEMBL262 | EC50 | 7.4 | 7.4 | 40.0 | 1 |
| Proto-oncogene Wnt-1 CHEMBL1255129 | EC50 | 5.47 | 5.47 | 3407.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | EC50 | = | 1.7 | nM | 8.77 | The screening assay for DYRK1A kinase activity : Each compound was dissolved in ... | - |
| Glycogen synthase kinase-3 beta | EC50 | = | 40.0 | nM | 7.4 | The screening for GSK3beta kinase activity: Each compound is dissolved in DMSO a... | - |
| Proto-oncogene Wnt-1 | EC50 | = | 3407.0 | nM | 5.47 | The screening assay for Wnt activity: The screening assay for Wnt activity is de... | - |
Data from ChEMBL 36 via Core Engine