Compound Detail
CHEMBL6006751
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6006751 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PMLHYFDQPIWSKJ-DJNXLDHESA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
290.4
MW (Da)
1.95
ALogP
3
HBA
1
HBD
34.0
PSA (Ų)
0.75
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 8.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neuronal acetylcholine receptor; alpha4/beta2 CHEMBL1907589 | Ki | 8.53 | 8.53 | 2.9 | 1 |
| Neuronal acetylcholine receptor; alpha3/beta4 CHEMBL1907594 | Ki | 7.02 | 7.02 | 95.0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 CHEMBL2492 | Ki | 5.4 | 5.4 | 3946.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neuronal acetylcholine receptor; alpha4/beta2 | Ki | = | 2.94 | nM | 8.53 | Binding to Nicotinic Receptor Subtypes: The binding of a group of compounds ment... | - |
| Neuronal acetylcholine receptor; alpha3/beta4 | Ki | = | 95.0 | nM | 7.02 | Binding to Nicotinic Receptor Subtypes: The binding of a group of compounds ment... | - |
| Neuronal acetylcholine receptor subunit alpha-7 | Ki | = | 3946.0 | nM | 5.4 | Binding to Nicotinic Receptor Subtypes: The binding of a group of compounds ment... | - |
Data from ChEMBL 36 via Core Engine