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Compound Detail

CHEMBL601438

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O=c1cc(Sc2ccccc2)n([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

Basic Information

ChEMBL ID CHEMBL601438
Phase Preclinical
Structure Type MOL
InChI Key NQKYRUKAZIGPCL-ICGCDAGXSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

592.3
MW (Da)
-0.35
ALogP
13
HBA
7
HBD
264.4
PSA (Ų)
0.14
QED
3
Ro5 Violations
10
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H19N2O15P3S
MW 592.31
Aromatic Rings 2
Heavy Atoms 36
NP-Likeness 0.69

Literature References

PubMed DOI Target Context # Activities
20095577 10.1021/jm901450d P2Y purinoceptor 2 1
20095577 10.1021/jm901450d P2Y purinoceptor 4 1
20095577 10.1021/jm901450d P2Y purinoceptor 6 1

Data from ChEMBL 36 via Core Engine