Compound Detail
CHEMBL6015887
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
O=C(O)CC[C@H](NC(=O)NC(Cc1ccc(NC(=O)c2cc(C(=O)O)cc(-n3cc(CCCF)nn3)c2)cc1)C(=O)O)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL6015887 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FSLUBFSMTPEHRI-HMTLIYDFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
628.6
MW (Da)
1.73
ALogP
9
HBA
7
HBD
250.1
PSA (Ų)
0.12
QED
2
Ro5 Violations
16
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate carboxypeptidase 2 CHEMBL1892 | Ki | 9.7 | 9.7 | 0.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate carboxypeptidase 2 | Ki | = | 0.2 | nM | 9.7 | Enzymatic Assay for In Vitro Evaluation of PSMA Inhibitors: The inhibitory activ... | - |
Data from ChEMBL 36 via Core Engine