Compound Detail
CHEMBL60162
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Basic Information
| ChEMBL ID | CHEMBL60162 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QVIFEFBNURQVKR-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
180.2
MW (Da)
-1.48
ALogP
5
HBA
4
HBD
80.9
PSA (Ų)
0.37
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 4.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tissue alpha-L-fucosidase CHEMBL4176 | Ki | 4.38 | 4.24 | 42000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tissue alpha-L-fucosidase | Ki | = | 42000.0 | nM | 4.38 | Compound was tested for the inhibitory activity against alpha-L-fucosidase from ... | - |
| Tissue alpha-L-fucosidase | Ki | = | 80000.0 | nM | 4.1 | Inhibition constant against Alpha-Fucosidase | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80649-6 | Tissue alpha-L-fucosidase | 1 |
| - | 10.1016/0960-894X(96)00356-3 | Tissue alpha-L-fucosidase | 1 |
Data from ChEMBL 36 via Core Engine