Compound Detail
CHEMBL6021264
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL6021264 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OTKYJPDWHNDEEY-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
381.5
MW (Da)
1.65
ALogP
6
HBA
1
HBD
86.9
PSA (Ų)
0.75
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A CHEMBL224 | Ki | 7.96 | 7.96 | 10.9 | 1 |
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | Ki | 7.9 | 7.9 | 12.7 | 1 |
| D(2) dopamine receptor CHEMBL217 | Ki | 6.29 | 6.29 | 514.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Ki | = | 10.9 | nM | 7.96 | Binding Activity Assay: Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D... | - |
| 5-hydroxytryptamine receptor 7 | Ki | = | 12.7 | nM | 7.9 | Binding Activity Assay: Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D... | - |
| D(2) dopamine receptor | Ki | = | 514.0 | nM | 6.29 | Binding Activity Assay: Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D... | - |
Data from ChEMBL 36 via Core Engine